Roles for substance P and gastrin-releasing peptide as neurotransmitters released by primary afferent pruriceptors

Recent studies support roles for neurokinin-1 (NK-1) and gastrin-releasing peptide (GRP) receptor-expressing spinal neurons in itch. We presently investigated expression of substance P (SP) and GRP in pruritogen-responsive primary sensory neurons and roles for these neuropeptides in itch signaling....

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Detalhes bibliográficos
Main Authors: Akiyama, Tasuku, Tominaga, Mitsutoshi, Davoodi, Auva, Nagamine, Masaki, Blansit, Kevin, Horwitz, Alexander, Carstens, Mirela Iodi, Carstens, E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567390/
https://ncbi.nlm.nih.gov/pubmed/23155177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00539.2012
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