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Reining in Polyoma Virus Associated Nephropathy: Design and Characterization of a Template Mimicking BK Viral Coat Protein Cellular Binding

The BK polyoma virus is a leading cause of chronic post kidney transplantation rejection. One target for therapeutic intervention is the initial association of the BK virus with the host cell. We hypothesize that the rate of BKV infection can be curbed by competitively preventing viral binding to ce...

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Autors principals: Audu, Christopher O., O’Hara, Bethany, Pellegrini, Maria, Wang, Lei, Atwood, Walter J., Mierke, Dale F.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567307/
https://ncbi.nlm.nih.gov/pubmed/23002929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300639d
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