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The C-terminal portion of the cleaved HT motif is necessary and sufficient to mediate export of proteins from the malaria parasite into its host cell

The malaria parasite exports proteins across its plasma membrane and a surrounding parasitophorous vacuole membrane, into its host erythrocyte. Most exported proteins contain a Host Targeting motif (HT motif) that targets them for export. In the parasite secretory pathway, the HT motif is cleaved by...

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Autori principali: Tarr, Sarah J, Cryar, Adam, Thalassinos, Konstantinos, Haldar, Kasturi, Osborne, Andrew R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567231/
https://ncbi.nlm.nih.gov/pubmed/23279267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12133
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