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CAG/CTG Repeats Alter Affinity for the Histone Core and Positioning of DNA in the Nucleosome
Trinucleotide repeats (TNRs) occur throughout the genome and their expansion has been linked to several neurodegenerative disorders, including Huntington’s Disease. TNRs have been studied using both oligonucleotides and plasmids; however, less is know about how repetitive DNA responds to genomic pac...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3567209/ https://ncbi.nlm.nih.gov/pubmed/23157165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi301416v |
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