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Photofrin Based Photodynamic Therapy and miR-99a Transfection Inhibited FGFR3 and PI3K/Akt Signaling Mechanisms to Control Growth of Human Glioblastoma In Vitro and In Vivo

Glioblastoma is the most common malignant brain tumor in humans. We explored the molecular mechanisms how the efficacy of photofrin based photodynamic therapy (PDT) was enhanced by miR-99a transfection in human glioblastoma cells. Our results showed almost similar uptake of photofrin after 24 h in d...

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Detalhes bibliográficos
Main Authors: Chakrabarti, Mrinmay, Banik, Naren L., Ray, Swapan K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567141/
https://ncbi.nlm.nih.gov/pubmed/23409016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055652
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