CREBH Determines the Severity of Sulpyrine-Induced Fatal Shock

Although the pyrazolone derivative sulpyrine is widely used as an antipyretic analgesic drug, side effects, including fatal shock, have been reported. However, the molecular mechanism underlying such a severe side effect is largely unclear. Here, we report that the transcription factor CREBH that is...

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Bibliografiske detaljer
Main Authors: Kamiyama, Naganori, Yamamoto, Masahiro, Saiga, Hiroyuki, Ma, Ji Su, Ohshima, Jun, Machimura, Sakaaki, Sasai, Miwa, Kimura, Taishi, Ueda, Yoshiyasu, Kayama, Hisako, Takeda, Kiyoshi
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567110/
https://ncbi.nlm.nih.gov/pubmed/23409047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055800
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