Mac-1 Directly Binds to the Endothelial Protein C-Receptor: A Link between the Protein C Anticoagulant Pathway and Inflammation?

OBJECTIVE: The endothelial protein C-receptor (EPCR) is an endothelial transmembrane protein that binds protein C and activated protein C (APC) with equal affinity, thereby facilitating APC formation. APC has anticoagulant, antiapoptotic and antiinflammatory properties. Soluble EPCR, released by the...

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Hlavní autoři: Fink, Katrin, Busch, Hans-Jörg, Bourgeois, Natascha, Schwarz, Meike, Wolf, Dennis, Zirlik, Andreas, Peter, Karlheinz, Bode, Christoph, von zur Muhlen, Constantin
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567096/
https://ncbi.nlm.nih.gov/pubmed/23408932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053103
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