Curcumin Potentiates Rhabdomyosarcoma Radiosensitivity by Suppressing NF-κB Activity

Ionizing radiation (IR) is an essential component of therapy for alveolar rhabdomyosarcoma. Nuclear factor-kappaB (NF-κΒ) transcription factors are upregulated by IR and have been implicated in radioresistance. We evaluated the ability of curcumin, a putative NF-κΒ inhibitor, and cells expressing ge...

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Bibliografiske detaljer
Main Authors: Orr, W. Shannon, Denbo, Jason W., Saab, Karim R., Ng, Catherine Y., Wu, Jianrong, Li, Kui, Garner, Jo Meagan, Morton, Christopher L., Du, Ziyun, Pfeffer, Lawrence M., Davidoff, Andrew M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567084/
https://ncbi.nlm.nih.gov/pubmed/23408929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051309
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