Isolation of Human Monoclonal Antibodies to the Envelope E2 Protein of Hepatitis C Virus and Their Characterization

We isolated and characterized two human monoclonal antibodies to the envelope E2 protein of hepatitis C virus (HCV). Lymphoblastoid cell lines stably producing antibodies were obtained by immortalizing peripheral blood mononuclear cells of a patient with chronic hepatitis C using Epstein-Barr virus....

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Detalhes bibliográficos
Main Authors: Shimizu, Yohko K., Hijikata, Minako, Oshima, Masamichi, Shimizu, Kazufumi, Alter, Harvey J., Purcell, Robert H., Yoshikura, Hiroshi, Hotta, Hak
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567033/
https://ncbi.nlm.nih.gov/pubmed/23409074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055874
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