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Massive-Scale Gene Co-Expression Network Construction and Robustness Testing Using Random Matrix Theory

The study of gene relationships and their effect on biological function and phenotype is a focal point in systems biology. Gene co-expression networks built using microarray expression profiles are one technique for discovering and interpreting gene relationships. A knowledge-independent thresholdin...

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Détails bibliographiques
Auteurs principaux: Gibson, Scott M., Ficklin, Stephen P., Isaacson, Sven, Luo, Feng, Feltus, Frank A., Smith, Melissa C.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567026/
https://ncbi.nlm.nih.gov/pubmed/23409071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055871
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