Pyrosequencing Dried Blood Spots Reveals Differences in HIV Drug Resistance between Treatment Naïve and Experienced Patients

Dried blood spots (DBS) are an alternative specimen collection format for HIV-1 genotyping. DBS produce HIV genotyping results that are robust and equivalent to plasma when using conventional sequencing methods. However, using tagged, pooled pyrosequencing, we demonstrate that concordance between pl...

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Detalhes bibliográficos
Main Authors: Ji, Hezhao, Li, Yang, Liang, Binhua, Pilon, Richard, MacPherson, Paul, Bergeron, Michèle, Kim, John, Graham, Morag, Van Domselaar, Gary, Sandstrom, Paul, Brooks, James
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567018/
https://ncbi.nlm.nih.gov/pubmed/23409150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056170
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