Circulating matrix metalloproteinase MMP-9 and MMP-2/TIMP-2 complex are associated with spontaneous early pregnancy failure

BACKGROUND: Trophoblast cell (CTB) invasion into the maternal endometrium plays a crucial role during human embryo implantation and placentation. This invasion is facilitated by the activity of matrix metalloproteinases, which are regulated by tissue inhibitors of MMPs (TIMPs). METHODS: This study c...

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Autori principali: Nissi, Ritva, Talvensaari-Mattila, Anne, Kotila, Vesa, Niinimäki, Maarit, Järvelä, Ilkka, Turpeenniemi-Hujanen, Taina
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566964/
https://ncbi.nlm.nih.gov/pubmed/23320481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7827-11-2
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