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Integrin α5β1-fimbriae binding and actin rearrangement are essential for Porphyromonas gingivalis invasion of osteoblasts and subsequent activation of the JNK pathway

BACKGROUND: Chronic periodontitis is an infectious disease of the periodontium, which includes the gingival epithelium, periodontal ligament and alveolar bone. The signature clinical feature of periodontitis is resorption of alveolar bone and subsequent tooth loss. The Gram-negative oral anaerobe, P...

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Bibliografiske detaljer
Main Authors: Zhang, Wenjian, Ju, Jun, Rigney, Todd, Tribble, Gena
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566952/
https://ncbi.nlm.nih.gov/pubmed/23305098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-13-5
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