Hereditary Nonpolyposis Colorectal Cancer (HNPCC)/Lynch Syndrome

BACKGROUND: Hereditary nonpolyposis colorectal cancer HNPCC, Lynch syndrome) is a genetic disease of autosomal dominant inheritance. It is caused by a mutation in one of four genes of the DNA mismatch repair system and confers a markedly increased risk for various types of cancer, particularly of th...

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Bibliografiske detaljer
Main Authors: Steinke, Verena, Engel, Christoph, Büttner, Reinhard, Schackert, Hans Konrad, Schmiegel, Wolff H, Propping, Peter
Format: Artigo
Sprog:Inglês
Udgivet: Deutscher Arzte Verlag 2013
Fag:
Review Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566622/
https://ncbi.nlm.nih.gov/pubmed/23413378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3238/arztebl.2013.0032
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