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Mis-expression of the BK K(+) channel disrupts suprachiasmatic nucleus circuit rhythmicity and alters clock-controlled behavior

In mammals, almost all aspects of circadian rhythmicity are attributed to activity in a discrete neural circuit of the hypothalamus, the suprachiasmatic nucleus (SCN). A 24-h rhythm in spontaneous firing is the fundamental neural intermediary to circadian behavior, but the ionic mechanisms that patt...

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Autors principals: Montgomery, Jenna R., Whitt, Joshua P., Wright, Breanne N., Lai, Michael H., Meredith, Andrea L.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566534/
https://ncbi.nlm.nih.gov/pubmed/23174562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00302.2012
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