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Simple Moment-Closure Model for the Self-Assembly of Breakable Amyloid Filaments
In this work, we derive a simple mathematical model from mass-action equations for amyloid fiber formation that takes into account the primary nucleation, elongation, and length-dependent fragmentation. The derivation is based on the principle of minimum free energy under certain constraints and is...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3566462/ https://ncbi.nlm.nih.gov/pubmed/23442904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.12.039 |
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