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Simple Moment-Closure Model for the Self-Assembly of Breakable Amyloid Filaments

In this work, we derive a simple mathematical model from mass-action equations for amyloid fiber formation that takes into account the primary nucleation, elongation, and length-dependent fragmentation. The derivation is based on the principle of minimum free energy under certain constraints and is...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Hong, Liu, Yong, Wen-An
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The Biophysical Society 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566462/
https://ncbi.nlm.nih.gov/pubmed/23442904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.12.039
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