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Genetic Analysis of Disheveled 2 and Disheveled 3 in Human Neural Tube Defects

Neural tube defects are severe malformations affecting 1/1,000 live births. The planar cell polarity pathway controls the neural tube closure and has been implicated in the pathogenesis of neural tube defects both in animal models and human cohorts. In mouse disruption of Dvl2 alone (Dvl2(−/−)) or D...

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Detalhes bibliográficos
Main Authors: De Marco, Patrizia, Merello, Elisa, Consales, Alessandro, Piatelli, Gianluca, Cama, Armando, Kibar, Zoha, Capra, Valeria
Formato: Artigo
Idioma:Inglês
Publicado em: Humana Press Inc 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566388/
https://ncbi.nlm.nih.gov/pubmed/22892949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-012-9871-9
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