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Optimized Phospholipid Bilayer Nanodiscs Facilitate High-Resolution Structure Determination of Membrane Proteins

Structural studies of membrane proteins are still hampered by difficulties of finding appropriate membrane mimicking media that maintain protein structure and function. Phospholipid nanodiscs seem promising to overcome the intrinsic problems of detergent containing environments. While nanodiscs can...

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Detalhes bibliográficos
Main Authors: Hagn, Franz, Etzkorn, Manuel, Raschle, Thomas, Wagner, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566289/
https://ncbi.nlm.nih.gov/pubmed/23294159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja310901f
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