Correspondence between in vivo (11)C-PiB PET amyloid imaging and post-mortem, region-matched assessment of plaques

The definitive Alzheimer’s disease diagnosis requires post-mortem confirmation of neuropathological hallmarks – amyloid-β (Aβ) plaques and neurofibrillary tangles (NFTs). The advent of radiotracers for amyloid imaging presents an opportunity to investigate amyloid deposition in vivo. The (11)C-Pitts...

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Main Authors: Driscoll, Ira, Troncoso, Juan C, Rudow, Gay, Sojkova, Jitka, Pletnikova, Olga, Zhou, Yun, Kraut, Michael A, Ferrucci, Luigi, Mathis, Chester A, Klunk, William E, O’Brien, Richard J, Davatzikos, Christos, Wong, Dean F, Resnick, Susan M
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566238/
https://ncbi.nlm.nih.gov/pubmed/22864813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-012-1025-1
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