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Targeted Single-cell microchemical analysis: MS-based peptidomics of individual paraformaldehyde-fixed and immunolabeled neurons

Pinpointing a specific cell from within a relatively uniform cell population to determine its chemical content presents a challenging bioanalytical task. Immunocytochemistry is the classical method used to localize specific molecules and hence, selected cells. Mass spectrometry also probes endogenou...

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Détails bibliographiques
Auteurs principaux: Neupert, Susanne, Rubakhin, Stanislav S., Sweedler, Jonathan V.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566229/
https://ncbi.nlm.nih.gov/pubmed/22921068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2012.05.023
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