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Targeted Single-cell microchemical analysis: MS-based peptidomics of individual paraformaldehyde-fixed and immunolabeled neurons
Pinpointing a specific cell from within a relatively uniform cell population to determine its chemical content presents a challenging bioanalytical task. Immunocytochemistry is the classical method used to localize specific molecules and hence, selected cells. Mass spectrometry also probes endogenou...
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Auteurs principaux: | , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
2012
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3566229/ https://ncbi.nlm.nih.gov/pubmed/22921068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2012.05.023 |
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