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Combined chemical and genetic approach to inhibit proteolysis by the proteasome
Regulated protein destruction by the proteasome is crucial for the maintenance of normal cellular homeostasis. Much of our understanding of proteasome function stems from the use of drugs that inhibit its activity. Curiously, despite the importance of proteasomal proteolysis, previous studies have f...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3566228/ https://ncbi.nlm.nih.gov/pubmed/20625982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/yea.1805 |
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