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Androgen Signaling Promotes Translation of TMEFF2 in Prostate Cancer Cells via Phosphorylation of the α Subunit of the Translation Initiation Factor 2

The type I transmembrane protein with epidermal growth factor and two follistatin motifs 2 (TMEFF2), is expressed mainly in brain and prostate. Expression of TMEFF2 is deregulated in prostate cancer, suggesting a role in this disease, but the molecular mechanism(s) involved in this effect are not cl...

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Bibliografiske detaljer
Main Authors: Overcash, Ryan F., Chappell, Vesna A., Green, Thomas, Geyer, Christopher B., Asch, Adam S., Ruiz-Echevarría, Maria J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566213/
https://ncbi.nlm.nih.gov/pubmed/23405127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055257
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