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Vitamin D(3) at 50x AI Attenuates the Decline in Paw Grip Endurance, but Not Disease Outcomes, in the G93A Mouse Model of ALS, and Is Toxic in Females

BACKGROUND: We previously demonstrated that dietary vitamin D(3) at 10x the adequate intake (AI) attenuates the decline in functional capacity in the G93A mouse model of ALS. We hypothesized that higher doses would elicit more robust changes in functional and disease outcomes. OBJECTIVE: To determin...

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Autors principals: Gianforcaro, Alexandro, Solomon, Jesse A., Hamadeh, Mazen J
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566148/
https://ncbi.nlm.nih.gov/pubmed/23405058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030243
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