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Molecular Analysis of the Prostacyclin Receptor’s Interaction with the PDZ1 Domain of Its Adaptor Protein PDZK1

The prostanoid prostacyclin, or prostaglandin I(2), plays an essential role in many aspects of cardiovascular disease. The actions of prostacyclin are mainly mediated through its activation of the prostacyclin receptor or, in short, the IP. In recent studies, the cytoplasmic carboxy-terminal domain...

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Detalhes bibliográficos
Main Authors: Birrane, Gabriel, Mulvaney, Eamon P., Pal, Rinku, Kinsella, B. Therese, Kocher, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566133/
https://ncbi.nlm.nih.gov/pubmed/23457445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053819
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