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CYLD Regulates RhoA Activity by Modulating LARG Ubiquitination
Rho family guanosine triphosphatases (GTPases), such as RhoA, Cdc42, and Rac1, play a fundamental role in various cellular processes. The activation of Rho proteins is catalyzed by guanine nucleotide-exchange factors (GEFs), which promote the exchange of GDP for GTP. The precise mechanisms regulatin...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3566121/ https://ncbi.nlm.nih.gov/pubmed/23405219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055833 |
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