Exposure of Chlorpromazine to 266 nm Laser Beam Generates New Species with Antibacterial Properties: Contributions to Development of a New Process for Drug Discovery

INTRODUCTION: Phenothiazines when exposed to white light or to UV radiation undergo a variety of reactions that result in degradation of parental compound and formation of new species. This process is slow and may be sped up with exposure to high energy light such as that produced by a laser. METHOD...

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Main Authors: Pascu, Mihail Lucian, Danko, Balazs, Martins, Ana, Jedlinszki, Nikoletta, Alexandru, Tatiana, Nastasa, Viorel, Boni, Mihai, Militaru, Andra, Andrei, Ionut Relu, Staicu, Angela, Hunyadi, Attila, Fanning, Seamus, Amaral, Leonard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566004/
https://ncbi.nlm.nih.gov/pubmed/23405212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055767
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