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A Novel Bayesian Change-point Algorithm for Genome-wide Analysis of Diverse ChIPseq Data Types

ChIPseq is a widely used technique for investigating protein-DNA interactions. Read density profiles are generated by using next-sequencing of protein-bound DNA and aligning the short reads to a reference genome. Enriched regions are revealed as peaks, which often differ dramatically in shape, depen...

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Autors principals: Xing, Haipeng, Liao, Willey, Mo, Yifan, Zhang, Michael Q.
Format: Artigo
Idioma:Inglês
Publicat: MyJove Corporation 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565849/
https://ncbi.nlm.nih.gov/pubmed/23271069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/4273
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