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RidA Proteins Prevent Metabolic Damage Inflicted by PLP-Dependent Dehydratases in All Domains of Life

Pyridoxal 5′-phosphate (PLP) is a coenzyme synthesized by all forms of life. Relevant to the work reported here is the mechanism of the PLP-dependent threonine/serine dehydratases, which generate reactive enamine/imine intermediates that are converted to keto acids by members of the RidA family of e...

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Detalhes bibliográficos
Main Authors: Lambrecht, Jennifer A., Schmitz, George E., Downs, Diana M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565831/
https://ncbi.nlm.nih.gov/pubmed/23386433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00033-13
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