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A Systematic Review of BH4 (Sapropterin) for the Adjuvant Treatment of Phenylketonuria

Context: Dietary management is the mainstay of effective treatment in PKU, but dietary restriction is difficult and additional treatment options are needed. Objective: To systematically review evidence regarding sapropterin (BH4) use as an adjunct to dietary restriction in individuals with PKU. Data...

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Detalhes bibliográficos
Main Authors: Lindegren, Mary Lou, Krishnaswami, Shanthi, Reimschisel, Tyler, Fonnesbeck, Christopher, Sathe, Nila A., McPheeters, Melissa L.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565680/
https://ncbi.nlm.nih.gov/pubmed/23430527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/8904_2012_168
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