A phylogenetic analysis using full-length viral genomes of South American dengue serotype 3 in consecutive Venezuelan outbreaks reveals novel NS5 mutation

Dengue virus currently causes 50-100 million infections annually. Comprehensive knowledge about the evolution of Dengue in response to selection pressure is currently unavailable, but would greatly enhance vaccine design efforts. In the current study, we sequenced 187 new dengue virus serotype 3(DEN...

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Autori principali: Schmidt, DJ, Pickett, BE, Camacho, D, Comach, G, Xhaja, K, Lennon, NJ, Rizzolo, K, de Bosch, N, Becerra, A, Nogueira, ML, Mondini, A, da Silva, EV, Vasconcelos, PF, Muñoz-Jordán, JL, Santiago, GA, Ocazionez, R, Gehrke, L, Lefkowitz, EJ, Birren, BW, Henn, MR, Bosch, I
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565618/
https://ncbi.nlm.nih.gov/pubmed/21964598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.meegid.2011.09.010
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