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Genetic background affects epistatic interactions between two beneficial mutations

The phenotypic effect of mutations can depend on their genetic background, a phenomenon known as epistasis. Many experimental studies have found that epistasis is pervasive, and some indicate that it may follow a general pattern dependent on the fitness effect of the interacting mutations. These stu...

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Autori principali: Wang, Yinhua, Díaz Arenas, Carolina, Stoebel, Daniel M., Cooper, Tim F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Royal Society 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565476/
https://ncbi.nlm.nih.gov/pubmed/22896270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsbl.2012.0328
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