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Inhibition of the Plasma Membrane Ca(2+) Pump by CD44 Receptor Activation of Tyrosine Kinases Increases the Action Potential Afterhyperpolarization in Sensory Neurons

The cytoplasmic Ca(2+) clearance rate affects neuronal excitability, plasticity, and synaptic transmission. Here, we examined the modulation of the plasma membrane Ca(2+) ATPase (PMCA) by tyrosine kinases. In rat sensory neurons grown in culture, the PMCA was under tonic inhibition by a member of th...

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Detalhes bibliográficos
Main Authors: Ghosh, Biswarup, Li, Yan, Thayer, Stanley A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565434/
https://ncbi.nlm.nih.gov/pubmed/21325503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5764-10.2011
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