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Effect of Repetitive Lysine-Tryptophan Motifs on the Eukaryotic Membrane

In a previous study, we synthesized a series of peptides containing simple sequence repeats, (KW)(n)–NH(2) (n = 2,3,4 and 5) and determined their antimicrobial and hemolytic activities, as well as their mechanism of antimicrobial action. However, (KW)(5) showed undesirable cytotoxicity against RBC c...

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Detalhes bibliográficos
Main Authors: Gopal, Ramamourthy, Lee, Jong Kook, Lee, Jun Ho, Kim, Young Gwon, Oh, Gwang Chae, Seo, Chang Ho, Park, Yoonkyung
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565372/
https://ncbi.nlm.nih.gov/pubmed/23340654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms14012190
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