Synthesis, Structure-Activity Relationships (SAR) and in Silico Studies of Coumarin Derivatives with Antifungal Activity

The increased incidence of opportunistic fungal infections, associated with greater resistance to the antifungal drugs currently in use has highlighted the need for new solutions. In this study twenty four coumarin derivatives were screened in vitro for antifungal activity against strains of Aspergi...

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Main Authors: de Araújo, Rodrigo S. A., Guerra, Felipe Q. S., de O. Lima, Edeltrudes, de Simone, Carlos A., Tavares, Josean F., Scotti, Luciana, Scotti, Marcus T., de Aquino, Thiago M., de Moura, Ricardo O., Mendonça, Francisco J. B., Barbosa-Filho, José M.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565321/
https://ncbi.nlm.nih.gov/pubmed/23306152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms14011293
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