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Synthetic hydrogel scaffold is an effective vehicle for delivery of INFUSE (rhBMP2) to critical-sized calvaria bone defects in rats

Medtronic’s INFUSE Bone Graft provides surgeons with a potent tool for stimulating bone formation. Current delivery vehicles that rely on Absorbable Collagen Sponges (ACS) require excessive quantities of the active ingredient in INFUSE, recombinant human Bone Morphogenic Protein-2 (rhBMP2), to achie...

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Detalhes bibliográficos
Main Authors: Mariner, Peter D., Wudel, Justin M., Miller, David E., Genova, E. Erin, Streubel, Sven-Olrik, Anseth, Kristi S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565235/
https://ncbi.nlm.nih.gov/pubmed/23070779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.22243
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