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Advanced Urothelial Carcinoma: Overcoming Treatment Resistance through Novel Treatment Approaches
The current standard of care for metastatic urothelial carcinoma is cisplatin-based chemotherapy but treatment is generally not curative. Mechanisms of resistance to conventional cytotoxic regimens include tumor cell drug efflux pumps, intracellular anti-oxidants, and enhanced anti-apoptotic signali...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3565214/ https://ncbi.nlm.nih.gov/pubmed/23390417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2013.00003 |
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