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Advanced Urothelial Carcinoma: Overcoming Treatment Resistance through Novel Treatment Approaches

The current standard of care for metastatic urothelial carcinoma is cisplatin-based chemotherapy but treatment is generally not curative. Mechanisms of resistance to conventional cytotoxic regimens include tumor cell drug efflux pumps, intracellular anti-oxidants, and enhanced anti-apoptotic signali...

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Hlavní autoři: Bambury, Richard M., Rosenberg, Jonathan E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565214/
https://ncbi.nlm.nih.gov/pubmed/23390417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2013.00003
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