A longitudinal pilot proton MRS investigation of the manic and euthymic states of bipolar disorder

Several lines of evidence implicate dysfunction in brain energy production as a key component of bipolar disorder. In particular, elevated brain lactate levels observed in this condition suggest a shift from aerobic to anaerobic metabolism, possibly as a result of mitochondrial abnormalities. Most p...

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Autori principali: Brady, R O, Cooper, A, Jensen, J E, Tandon, N, Cohen, B, Renshaw, P, Keshavan, M, Öngür, D
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565206/
https://ncbi.nlm.nih.gov/pubmed/22968227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2012.84
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