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Isolation and Preliminary Characterization of Temperature-Sensitive Mutants of Influenza Virus

Isolation of temperature-sensitive (ts) mutants was attempted from the WSN strain of influenza A virus which was grown and assayed in MDBK cells. After growth of wild-type virus in the presence of 5-fluorouracil, 15 ts mutants were selected for which the ratio of plaquing efficiency at 39.5 C to tha...

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Autors principals: Sugiura, A., Tobita, K., Kilbourne, Edwin D.
Format: Artigo
Idioma:Inglês
Publicat: 1972
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC356514/
https://ncbi.nlm.nih.gov/pubmed/4673486
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