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Phosphoglycerate dehydrogenase induces glioma cells proliferation and invasion by stabilizing forkhead box M1
Phosphoglycerate dehydrogenase (PHGDH) is the first enzyme branching from glycolysis in the three-step serine biosynthetic pathway. Recent evidence has shown that PHGDH is amplified in human breast cancer and melanoma and plays a key role in cancer metabolism. However, PHGDH expression in glioma and...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer US
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3565087/ https://ncbi.nlm.nih.gov/pubmed/23229761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-012-1018-x |
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