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RNA Polymerase II Mutations Conferring Defects in Poly(A) Site Cleavage and Termination in Saccharomyces cerevisiae

Transcription termination by RNA polymerase (Pol) II is an essential but poorly understood process. In eukaryotic nuclei, the 3′ ends of mRNAs are generated by cleavage and polyadenylation, and the same sequence elements that specify that process are required for downstream release of the polymerase...

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Bibliographische Detailangaben
Hauptverfasser: Kubicek, Charles E., Chisholm, Robert D., Takayama, Sachiko, Hawley, Diane K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Genetics Society of America 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564978/
https://ncbi.nlm.nih.gov/pubmed/23390594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.112.004531
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