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Chronic Endocannabinoid System Stimulation Induces Muscle Macrophage and Lipid Accumulation in Type 2 Diabetic Mice Independently of Metabolic Endotoxaemia

AIMS: Obesity and type 2 diabetes are characterised by low-grade inflammation, metabolic endotoxaemia (i.e., increased plasma lipopolysaccharides [LPS] levels) and altered endocannabinoid (eCB)-system tone. The aim of this study was to decipher the specific role of eCB-system stimulation or metaboli...

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Bibliografische gegevens
Hoofdauteurs: Geurts, Lucie, Muccioli, Giulio G., Delzenne, Nathalie M., Cani, Patrice D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564911/
https://ncbi.nlm.nih.gov/pubmed/23393605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055963
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