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Adsorption behavior of a human monoclonal antibody at hydrophilic and hydrophobic surfaces
One aspiration for the formulation of human monoclonal antibodies (mAb) is to reach high solution concentrations without compromising stability. Protein surface activity leading to instability is well known, but our understanding of mAb adsorption to the solid-liquid interface in relevant pH and sur...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3564877/ https://ncbi.nlm.nih.gov/pubmed/23196810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.22522 |
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