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Selection and Preliminary Characterization of Temperature-Sensitive Mutants of Type 5 Adenovirus

Eight temperature-sensitive (ts) mutants that replicate normally at 32 C but poorly, if at all, at 39.5 C have been isolated from mutagenized stocks of a wild-type strain of type 5 adenovirus. Three mutagens were employed: nitrous acid, hydroxylamine, and nitrosoguanidine. Ts mutants were isolated f...

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Autors principals: Ensinger, Marcia J., Ginsberg, Harold S.
Format: Artigo
Idioma:Inglês
Publicat: 1972
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC356471/
https://ncbi.nlm.nih.gov/pubmed/4627331
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