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Lamin A tail modification by SUMO1 is disrupted by familial partial lipodystrophy–causing mutations

Lamin filaments are major components of the nucleoskeleton that bind LINC complexes and many nuclear membrane proteins. The tail domain of lamin A directly binds 21 known partners, including actin, emerin, and SREBP1, but how these interactions are regulated is unknown. We report small ubiquitin-lik...

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Bibliografski detalji
Glavni autori: Simon, Dan N., Domaradzki, Tera, Hofmann, Wilma A., Wilson, Katherine L.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564541/
https://ncbi.nlm.nih.gov/pubmed/23243001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-07-0527
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