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Microsatellite Instability in Sarcoma: Fact or Fiction?

Microsatellite instability (MSI) is a unique molecular abnormality, indicative of a deficient DNA mismatch repair (MMR) system. Described and characterized in the colorectal cancer literature, the MSI-positive phenotype is predictive of disease susceptibility, pathogenesis, and prognosis. The clinic...

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Detalles Bibliográficos
Main Authors: Monument, Michael J., Lessnick, Stephen L., Schiffman, Joshua D., Randall, Rl. Tx.
Formato: Artigo
Idioma:Inglês
Publicado: International Scholarly Research Network 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564276/
https://ncbi.nlm.nih.gov/pubmed/23401795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5402/2012/473146
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