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Genome-scale engineering for systems and synthetic biology

Genome-modification technologies enable the rational engineering and perturbation of biological systems. Historically, these methods have been limited to gene insertions or mutations at random or at a few pre-defined locations across the genome. The handful of methods capable of targeted gene editin...

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Detalhes bibliográficos
Main Authors: Esvelt, Kevin M, Wang, Harris H
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564264/
https://ncbi.nlm.nih.gov/pubmed/23340847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2012.66
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