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Altering SARS Coronavirus Frameshift Efficiency Affects Genomic and Subgenomic RNA Production

In previous studies, differences in the amount of genomic and subgenomic RNA produced by coronaviruses with mutations in the programmed ribosomal frameshift signal of ORF1a/b were observed. It was not clear if these differences were due to changes in genomic sequence, the protein sequence or the fre...

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Detalhes bibliográficos
Main Authors: Plant, Ewan P., Sims, Amy C., Baric, Ralph S., Dinman, Jonathan D., Taylor, Deborah R.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564121/
https://ncbi.nlm.nih.gov/pubmed/23334702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v5010279
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