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Fundamental roles of the innate-like repertoire of natural antibodies in immune homeostasis

The composition of the early immune repertoire is biased with prominent expression of spontaneously arising B cell clones that produce IgM with recurrent and often autoreactive binding specificities. Amongst these naturally arising antibodies (NAbs) are IgM antibodies that specifically recognized am...

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Bibliographic Details
Main Authors: Vas, Jaya, Grönwall, Caroline, Silverman, Gregg J.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564042/
https://ncbi.nlm.nih.gov/pubmed/23386848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00004
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