Genomics of ADME gene expression: mapping expression quantitative trait loci relevant for absorption, distribution, metabolism and excretion of drugs in human liver

Expression quantitative trait loci (eQTL) analysis is a powerful approach toward identifying genetic loci associated with quantitative changes in gene expression. We applied genome-wide association analysis to a data set of >300 000 single-nucleotide polymorphisms and >48 000 mRNA expression p...

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Bibliografiske detaljer
Main Authors: Schröder, A, Klein, K, Winter, S, Schwab, M, Bonin, M, Zell, A, Zanger, U M
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564008/
https://ncbi.nlm.nih.gov/pubmed/22006096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2011.44
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