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Tumor suppressor WWOX binds to ΔNp63α and sensitizes cancer cells to chemotherapy
The WWOX tumor suppressor is a WW domain-containing protein. Its function in the cell has been shown to be mediated, in part, by interacting with its partners through its first WW (WW1) domain. Here, we demonstrated that WWOX via WW1 domain interacts with p53 homolog, ΔNp63α. This protein–protein in...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3564006/ https://ncbi.nlm.nih.gov/pubmed/23370280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.6 |
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